Methoxybenzoic acids and derivatives
Medchemexpress LLC (S)-5-Methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride | 93601-86-6 | 99.99% | 255.78 | 10 G
(S)-5-Methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride is a chemical compound primarily used as a drug intermediate. It is essential for the synthesis of various active pharmaceutical compounds.
- Drug intermediate for synthesis of active compounds.
Medchemexpress LLC Hydroxy-PEG4-acid 10g | 937188-59-5 | 10 G
Hydroxy-PEG4-acid is a four-unit polyethylene glycol (PEG) linker with a terminal hydroxyl and a carboxylic acid, supplied as a purified reagent for bioconjugation and linker synthesis. It is suitable for use as a non-cleavable spacer in antibody-drug conjugates (ADCs), and as a PEG-based linker in PROTACs and related chemistries.
- Four-unit PEG spacer with terminal hydroxyl and carboxylic acid.
- High purity suitable for research use.
- Available in multiple pack sizes, including 10 G.
- Stable when stored at recommended temperatures for long-term use.
- Useful for ADC linker construction, PROTAC assembly, and general bioconjugation.
Medchemexpress LLC 2-Hydroxy-4-methoxybenzoic acid | 2237-36-7 | 99.6% | C8H8O4 | 5 G
2-Hydroxy-4-methoxybenzoic acid, or 4-Methoxysalicylic Acid, is a phenolic compound from plants like Hemidesmus indicus, known for its diverse biological activities.
- Isolated from natural plant sources
- Exhibits anti-diabetic, hypolipidemic, and hepatoprotective activities
- Demonstrates anti-snake venom properties
- Used in research for diabetes, liver, immune-related diseases, and snake venom poisoning
- Evaluated for cytotoxicity against RAW264.7 cells
Chemscene ChemScene | 2-Amino-3-methoxybenzoic acid | 25G | CS-B0779 | 0.98 | 3177-80-8| MFCD00075178 | 167.16
ChemScene | 2-Amino-3-methoxybenzoic acid | 25G | CS-B0779 | 0.98 | 3177-80-8| MFCD00075178 | 167.16
Apexbio Technology LLC Ro 08-2750 37854-59-4 1mg
Ro 08-2750 (CAS 37854-59-4) is a small molecule antagonist of nerve growth factor (NGF) that selectively inhibits NGF binding to the p75 neurotrophin receptor (p75NTR) over TrkA With an IC50 of 1 M for NGF binding Ro 08-2750 induces a conformational change in NGF preventing its interaction with p75NTR while sparing TrkA association at lower concentrations In vitro studies demonstrate that Ro 08-2750 modulates NGF-mediated signaling including suppression of NGF-induced apoptosis in SK-N-MC cells and enhancement of TrkA pathway activity in PC12 cells This compound serves as a valuable tool for investigating the distinct roles of p75NTR and TrkA in neuronal apoptosis differentiation and axonal growth
Medchemexpress LLC 5-methoxy-5-oxopentanoic acid | 1501-27-5 | MFCD00004409 | 99.3% | 146.14 g/mol | C6H10O4 | 10 G
5-Methoxy-5-oxopentanoic acid is an endogenous metabolite offered as a high-purity analytical standard for research, metabolomics, and analytical method development. The product is supplied in multiple pack sizes to accommodate small-scale assays and larger preparative needs, and is characterized with specified purity and physical property data for use as a reference material.
- Endogenous metabolite suitable for metabolomics studies.
- High purity: 99.28%.
- Molecular formula C6H10O4; molecular weight 146.14 g/mol.
- Available in multiple pack sizes, including a 10 g option, for experimental flexibility.
- Colorless to light yellow liquid with density 1.164 g/cm3.
- Intended for use as an analytical reference standard and for method development.
Medchemexpress LLC 2,6-Dimethoxybenzoic acid | 1466-76-8 | 99.39% | C9H10O4 | 10 G
2,6-Dimethoxybenzoic acid is an endogenous metabolite and belongs to the class of o-methoxybenzoic acids and derivatives. With a molecular weight of 182.17, it presents as an off-white to gray solid. This compound is suitable for various research applications.
- Endogenous metabolite
- Inhibitor in metabolic enzyme/protease pathway
- Appearance: solid, off-white to gray
- Purity: 99.39%
- Soluble in DMSO: 100 mg/mL (548.94 mM)
- Molecular weight: 182.17
- For research use only
Medchemexpress LLC 3-ethoxy-3-oxopropanoic acid (potassium) | 6148-64-7 | MFCD00035603 | 99.9% | 170.21 g/mol | C5H7KO4 | 10g
3-Ethoxy-3-oxopropanoic acid potassium is an endogenous metabolite 3-Ethoxy-3-oxopropanoic acid potassium promotes plant growth[1][2]
Medchemexpress LLC Sjf-1521 | 2230821-40-4 | >98.0% | C57H61ClFN7O9S | 10MG
SJF-1521 is a selective EGFR PROTAC degrader that induces proteasomal degradation of EGFR in OVCAR8 cells and is used for tumor research and cellular pathway studies. It couples an EGFR-binding ligand to a VHL-recruiting moiety to promote targeted ubiquitination and clearance of the receptor.
- Selective EGFR degrader enabling modulation of receptor levels.
- Demonstrated to induce EGFR degradation in OVCAR8 cells.
- Dual mechanism: EGFR binding and VHL recruitment for proteasomal degradation.
- Suitable for tumor biology and signal transduction research in cell models.
- Reported high purity suitable for biochemical and cellular assays (≥98% HPLC).
- Available in multiple research-scale pack sizes for experimental flexibility.
![Medchemexpress LLC N-[5-[4-chloro-3-(2-hydroxyethylsulfamoyl)phenyl]-4-methyl-1,3-thiazol-2-yl]acetamide | 593960-11-3 | 99.7% | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000233261.png-250.jpg)
Medchemexpress LLC N-[5-[4-chloro-3-(2-hydroxyethylsulfamoyl)phenyl]-4-methyl-1,3-thiazol-2-yl]acetamide | 593960-11-3 | 99.7% | 1 MG
PIK-93 is a synthetic small-molecule inhibitor of phosphatidylinositol 4-kinase IIIβ (PI4KIIIβ) with a reported IC50 of 19 nM. It also inhibits class I PI3K isoforms and is used as a research tool to study phosphoinositide signaling, membrane trafficking, and viral replication.
- Potent PI4KIIIβ inhibitor (IC50 19 nM).
- Inhibits PI3Kγ and PI3Kα (IC50 16 nM and 39 nM).
- Soluble in DMSO (100 mg/mL); in vivo formulation protocols provided.
- Supplied as a white to off-white solid with high purity.
- Used in cellular assays to probe lipid signaling and viral replication.
Medchemexpress LLC 2-Hydroxy-4-methoxybenzaldehyde | 673-22-3 | 152.15 | 25 G
2-Hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor and an isomer of Vanillin. It can be used to synthesize Urolithin M7 and inhibits the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) by mushroom tyrosinase with an ID50 of 4.3 μg/mL (0.03 mM). It appears as an off-white to light brown solid, being a solid below 41°C and liquid above 43°C.
- Potent tyrosinase inhibitor
- Isomer of vanillin
- Synthesizes urolithin M7
- Inhibits L-DOPA oxidation
- Off-white to light brown color
- Solid below 41°C, liquid above 43°C
- Molecular weight of 152.15
- Chemical formula C8H8O3